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Updated: Feb 22, 2026
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Published on: August 8, 2019
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Increased double product on Monday morning during work
Genjiro Kimura1, Nobutaka Inoue1, Hiroumi Mizuno1
1Asahi Rosai Hospital, Japan Organization of Occupational Health and Safety, Aichi, Japan.
Summary
Cardiovascular events may increase on Monday mornings. Researchers found no weekly blood pressure changes, but a higher double product (systolic blood pressure × heart rate) on Mondays, especially in the morning.
Area of Science:
- Cardiology
- Chronobiology
- Hypertension Research
Background:
- Cardiovascular events show a higher incidence on Monday mornings, particularly in the young working demographic.
- Hypertension is a significant risk factor for cardiovascular events.
Purpose of the Study:
- To investigate if blood pressure is elevated on Monday mornings in a working population.
- To explore the relationship between weekly and circadian rhythms and cardiovascular risk markers.
Main Methods:
- Monitoring of blood pressure and heart rate throughout the week.
- Analysis of weekly and circadian patterns in cardiovascular parameters.
- Calculation of the double product (systolic blood pressure × heart rate).
Main Results:
- No significant weekly rhythms were observed in blood pressure itself.
- A significant interaction was found between the double product and weekly/circadian rhythms.
- The double product was elevated on Mondays, particularly in the morning hours.
Conclusions:
- The study did not find weekly blood pressure rhythms but identified a heightened double product on Monday mornings.
- Increased double product may contribute to the observed Monday morning preference for cardiovascular events.
- Further research is needed to confirm the causal link between elevated double product and Monday morning cardiovascular events.
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