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Red cell distribution width is correlated with extensive coronary artery disease in patients with diabetes mellitus

Atac Celik1, Metin Karayakali1, Fatih Altunkas1

  • 1Department of Cardiology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey.

Cardiovascular Journal of Africa
|September 15, 2017
PubMed

Insights

Red cell distribution width (RDW) is elevated in diabetic patients with coronary artery disease (CAD). Higher RDW levels correlate with more extensive and complex coronary artery lesions in this population.

Area of Science:

  • Cardiology
  • Diabetology
  • Hematology

Background:

  • Previous research suggests a link between red cell distribution width (RDW) and adverse outcomes in coronary artery disease (CAD).
  • The association between RDW and the extent of CAD in diabetic patients remains less understood.

Purpose of the Study:

  • To investigate the relationship between RDW and the extensiveness of CAD in patients with diabetes mellitus (DM).

Main Methods:

  • Retrospective analysis of 233 diabetic patients who underwent coronary angiography.
  • Gensini scores and triple-vessel disease were assessed to quantify CAD extensiveness.

Main Results:

  • RDW was significantly higher in diabetic patients with CAD (p < 0.001).
  • Elevated RDW (> 13.25%) was associated with higher Gensini scores, increased obstructive CAD, and a greater prevalence of triple-vessel disease (p ≤ 0.001).
  • RDW showed a positive correlation with CAD extensiveness (r < 0.468, p < 0.001).

Conclusions:

  • RDW levels are increased in diabetic patients with CAD.
  • Higher RDW values indicate more extensive and complex coronary artery lesions in this patient group.
Abstract

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