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Motor and Sensory Areas of the Cortex

Motor and Sensory Areas of the Cortex

The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
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The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....

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Related Experiment Video

Updated: Feb 22, 2026

Video-oculography in Mice

Video-oculography in Mice

Published on: July 19, 2012

A Sensorimotor Circuit in Mouse Cortex for Visual Flow Predictions.

Marcus Leinweber¹, Daniel R Ward¹, Jan M Sobczak¹

¹Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.

|September 15, 2017

Summary

This summary is machine-generated.

Motor cortex signals predict visual flow in the primary visual cortex (V1). Neural activity in V1 adapts to experience, matching visual flow predictions during navigation.

Keywords:

A24b anterior cingulate cortex predictive coding sensorimotor integration visual cortex

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Last Updated: Feb 22, 2026

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Published on: July 19, 2012

Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging

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Using Looming Visual Stimuli to Evaluate Mouse Vision

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Published on: June 13, 2019

Area of Science:

Neuroscience
Computational Neuroscience
Systems Neuroscience

Background:

The brain's cortex processes information hierarchically.
Top-down signals modulate sensory responses based on attention and context.

Purpose of the Study:

Investigate the role of top-down signals from A24b/secondary motor cortex (M2) to primary visual cortex (V1).
Determine if these signals predict visual flow based on motor output.

Main Methods:

Imaging neural activity in mouse V1 during virtual environment navigation.
Analyzing the correlation between A24b/M2 axon activity, locomotion, and visual flow.
Training mice in a visually inverted environment to observe adaptive neural responses.

Main Results:

A24b/M2 activity in V1 strongly correlated with locomotion and visual flow in an experience-dependent manner.
Neural activity patterns reversed when mice navigated an inverted environment, matching the altered visual flow.
Findings support a predictive coding model for visual processing.

Conclusions:

Top-down input from A24b/M2 to V1 predicts visual flow based on motor output.
Experience shapes these predictive signals in a manner consistent with predictive coding.
This study elucidates a mechanism for integrating motor commands and sensory feedback in visual processing.