Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

Issues And Trends In Healthcare Delivery System

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...

Pharmacogenomics: Identification of New Drug Targets

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

Pharmacogenetics and Pharmacogenomics: Overview

Pharmacogenetics and Pharmacogenomics: Overview

Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...

Genome-wide Association Studies-GWAS

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lessons learnt from moving an intensive care unit into a new hospital.

Journal of the Intensive Care Society·2025

Same author

Communicating clearly about data sharing in genomics.

Human genomics·2025

Same author

Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease.

Journal of neuropsychology·2025

Same author

Development and in-vitro assessment of novel oxygen-releasing feed additives to reduce enteric ruminant methane emissions.

The Science of the total environment·2024

Same author

Ethical considerations in prenatal genomic testing.

Best practice & research. Clinical obstetrics & gynaecology·2024

Same author

The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis.

Rheumatology (Oxford, England)·2023

Search research articles

Related Experiment Video

Updated: Feb 22, 2026

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

Genomic medicine and data sharing.

Sobia Raza¹, Alison Hall¹

¹PHG Foundation, 2 Worts Causeway, Cambridge, CB1 8RN, UK.

British Medical Bulletin

|September 16, 2017

Summary

This summary is machine-generated.

Effective genomic data sharing is crucial for advancing genomic medicine in the UK. Current challenges include technical debates and public trust, hindering progress in clinical care and research.

Keywords:

clinical care data sharing genomics policy

More Related Videos

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

Microbial Communities in Nature and Laboratory - Interview

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

Related Experiment Videos

Last Updated: Feb 22, 2026

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

Microbial Communities in Nature and Laboratory - Interview

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

Area of Science:

Genomic Medicine
Health Data Policy

Background:

Effective data sharing is vital for high-quality genomic services and advancing genomic medicine in the UK.
Despite its importance, data sharing is not effectively implemented across clinical specialities.

Purpose of the Study:

To highlight the necessity of data sharing for genomic medicine.
To identify barriers and opportunities for improving data sharing in the UK.

Main Methods:

Review of original papers, reviews, guidelines, policy papers, and web resources.
Analysis of areas of agreement, controversy, and opportunities for developing research.

Main Results:

Agreement exists on the need for infrastructure, policies, and professional/public acceptance for genomic data sharing.
Controversy surrounds technical approaches and safeguards, impacting trust and confidence.
Policy developments offer opportunities to establish effective and safeguarded data sharing systems.

Conclusions:

Addressing technical debates and enhancing public trust are critical for enabling effective genomic data sharing.
Developing robust mechanisms for public trust is a timely research priority.
Policy and infrastructure improvements are needed to support proportionate and safeguarded data sharing for genomic medicine.