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Updated: Feb 22, 2026
A Tetracycline-regulated Cell Line Produces High-titer Lentiviral Vectors that Specifically Target Dendritic Cells
Published on: June 19, 2013
Development and Optimization of a High Titer Recombinant Lentivirus System
Austin Storck1, James Ludtke1, Leisha Kopp1
1Mirus Bio LLC, Madison, Wisconsin, USA.
Abstract:
To enable simple and effective high titer recombinant lentivirus production, we examined key parameters for the generation of lentivirus including: transfection optimization, media change, incubation time and DNA vector selection. These results illustrate the importance of optimizing transfection processes for high titer recombinant lentivirus production.
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