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Updated: Feb 22, 2026

Utilizing the Precision-Cut Lung Slice to Study the Contractile Regulation of Airway and Intrapulmonary Arterial Smooth Muscle
Published on: May 5, 2022
Age associated changes in peripheral airway smooth muscle mass of healthy horses
M Bullone1, M Pouyet1, J-P Lavoie1
1Department of Clinical Sciences, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, Quebec J2S 2M2, Canada.
Abstract:
Peripheral airway smooth muscle (ASM) mass is increased in severe equine asthma, but no information is available on age related changes in ASM. In this study, peripheral ASM dimensions were determined in healthy horses of different ages. The thickness of the peripheral ASM layer was constant in horses of different ages, but ASM occupied a greater proportion of the inner wall area in young horses compared to older horses. This finding suggests that equine airways experience a decrease in the relative abundance of ASM with age.
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