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Updated: Feb 22, 2026

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
Published on: April 7, 2023
Luteal phase support in intrauterine insemination cycles
İsmet Gün1, Özkan Özdamar2, Ali Yılmaz1
1Gülhane Military Medical Academy, Haydarpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey.
Abstract:
Intrauterine insemination (IUI) treatment aims to increase the rate of conception by increasing the chances that the maximum number of healthy sperm reach the site of fertilization. IUI with controlled ovarian stimulation is frequently used in assisted reproduction practice. Although widely used, the efficacy of luteal support in IUI remains controversial. In this article, we aimed to review what we know regarding luteal support in IUI cycles and to adjudicate about the clinical use and benefits of this treatment. Based on the study results available in the literature, it appears to be beneficial to supplement the luteal phase in gonadotropin-stimulated IUI cycles that yield more than one follicle.
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