Related Experiment Video
Updated: Feb 22, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Importance of Accurate Diagnosis in Pyoderma Gangrenosum
Yoon Soo Kim1, Han Kyeol Kim1, Yea Sik Han1
1Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine, Busan, Korea.
Abstract:
Pyoderma gangrenosum is a rare inflammatory reactive dermatosis marked by painful cutaneous ulcers. Diagnosis of pyoderma gangrenosum is usually made based on past medical history and after the exclusion of other possible diseases based on the clinical manifestations of the lesion. Diseases that show rapid progression to necrosis and that should not be misdiagnosed as pyoderma gangrenosum include malignant neoplasms and necrotizing fasciitis. Immunosuppressive agents such as steroids and cyclosporine are considered first-line therapy. Surgical removal of the necrotic tissues is contraindicated, as it may further induce immune reaction and promote ulcer to enlarge. Here, we present a case to encourage plastic surgeons to consider pyodermagangrenosum in the differential diagnosis of idiopathic ulcers. Satisfactory outcomes for patients with pyodermagangrenosum may be expected when using steroids and immunosuppressive agents during the early stage of the disease.
Insights
Pyoderma gangrenosum, a rare ulcerative skin condition, requires prompt diagnosis by excluding other diseases. Early treatment with immunosuppressants like steroids offers favorable outcomes for patients.
Area of Science:
- Dermatology
- Immunology
- Plastic Surgery
Background:
- Pyoderma gangrenosum is a rare, inflammatory skin disease characterized by painful ulcers.
- Diagnosis relies on clinical presentation and excluding other conditions like cancer or necrotizing fasciitis.
- Surgical debridement is contraindicated due to potential worsening of the ulcer.
Purpose of the Study:
- To highlight the importance of considering pyoderma gangrenosum in the differential diagnosis of idiopathic ulcers.
- To encourage plastic surgeons to include this diagnosis when evaluating non-healing wounds.
- To emphasize early intervention for better patient outcomes.
Main Methods:
- Case presentation of a patient with pyoderma gangrenosum.
- Review of diagnostic criteria and treatment protocols for pyoderma gangrenosum.
- Discussion of differential diagnoses for rapidly progressing ulcerative lesions.
Main Results:
- The case illustrates a successful outcome using early immunosuppressive therapy.
- Delayed diagnosis and inappropriate surgical intervention can lead to disease progression.
- Steroids and immunosuppressive agents are effective in managing pyoderma gangrenosum.
Conclusions:
- Plastic surgeons should consider pyoderma gangrenosum in cases of idiopathic ulcers.
- Early diagnosis and treatment with immunosuppressants are crucial for managing pyoderma gangrenosum.
- Prompt medical management leads to satisfactory outcomes and prevents ulcer enlargement.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Documentation of Nursing Diagnosis
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Pneumonia III: Complications and Assessment
Acute Pancreatitis II: Clinical Manifestations and Management