A Giant Keratoacanthoma Treated with Surgical Excision

Area of Science:

• Dermatology
• Surgical Oncology

Background:

• Keratoacanthoma is a rapidly growing cutaneous tumor, typically self-involuting.
• Giant keratoacanthoma is a rare variant, defined by lesions >20 mm.
• Distinguishing keratoacanthoma from squamous cell carcinoma is clinically important.

Purpose of the Study:

• To report the first case of giant keratoacanthoma treated with surgical excision in Korea.
• To discuss clinical and histopathological features of keratoacanthoma.
• To review the literature on giant keratoacanthoma.

Main Methods:

• A 56-year-old man presented with a rapidly growing right cheek tumor.
• Surgical excision under general anesthesia was performed.
• Reconstruction utilized a Limberg flap.
• Intraoperative frozen section and final histopathology were analyzed.

Main Results:

• Final histopathology confirmed the lesion as keratoacanthoma.
• Intraoperative frozen section suggested well-differentiated squamous cell carcinoma.
• The giant keratoacanthoma was completely excised.

Conclusions:

• Giant keratoacanthoma requires complete surgical excision.
• Accurate histopathological diagnosis is crucial, as intraoperative findings can be misleading.
• This case contributes to the understanding of giant keratoacanthoma management.