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Updated: Feb 22, 2026

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Chondroid Syringoma on Face.

Kyung Hee Min1, Jin Hwan Byun1, Jung Soo Lim1

  • 1Department of Plastic and Reconstructive Surgery, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.

Archives of Craniofacial Surgery
|September 16, 2017
PubMed
Summary
This summary is machine-generated.

Chondroid syringoma, a rare skin tumor, presents as a nodular or cystic lesion on the head and neck. Accurate diagnosis through clinical, sonographic, and histological analysis is crucial for effective management.

Keywords:
Facial neoplasmPleomorphic adenomaSkin neoplasm

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Area of Science:

  • Dermatology
  • Pathology
  • Oncology

Background:

  • Chondroid syringoma is a rare cutaneous mixed tumor (<0.1% incidence), often found on the head and neck.
  • It comprises both mesenchymal and epithelial cells, frequently misdiagnosed as epidermal cysts.
  • Malignant variants exist, underscoring the need for accurate diagnosis and management.

Purpose of the Study:

  • To report the clinical, sonographic, and histological features of chondroid syringoma.
  • To aid clinicians in diagnosing and managing similar facial lesions.
  • To highlight the importance of early and accurate diagnosis for patient outcomes.

Main Methods:

  • Retrospective analysis of 5 chondroid syringoma cases.
  • Review of clinical presentations, sonographic findings, and histopathological examinations.
  • Surgical excision and subsequent microscopic evaluation of tumor components.

Main Results:

  • Lesions typically appeared as round, firm, nodular, or cystic with heterogeneous, well-marginated sonographic features.
  • All tumors were successfully treated with simple excision.
  • Histology confirmed well-circumscribed tumors with epithelial, myoepithelial, and stromal components, including myxoid stroma.

Conclusions:

  • Chondroid syringoma diagnosis relies on integrating clinical, sonographic, and histological data.
  • Simple excision is an effective treatment modality.
  • This case series provides valuable insights for differentiating and managing analogous facial lesions.