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Published on: October 15, 2021
Emergency Neurological Life Support: Intracranial Hypertension and Herniation
Rhonda Cadena1, Michael Shoykhet2, Jonathan J Ratcliff3
1Departments of Neurology, Neurosurgery, and Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA. rhonda.cadena@unc.edu.
Insights
Recognizing "brain codes" like intracranial hypertension and brain herniation is crucial for immediate treatment. This Emergency Neurological Life Support protocol provides a standardized, evidence-based algorithm for managing these critical neurological events.
Area of Science:
- Neurology
- Critical Care Medicine
- Emergency Medicine
Background:
- Sustained intracranial hypertension and acute brain herniation represent critical neurological emergencies, termed "brain codes."
- These conditions necessitate prompt recognition and intervention to avert irreversible brain damage and mortality.
- Effective management parallels organized, stepwise approaches used in other critical events like cardiac arrest.
Purpose of the Study:
- To establish an evidence-based, standardized protocol for the evaluation and management of intracranial hypertension and brain herniation.
- To guide healthcare professionals in the organized implementation of a stepwise algorithm for "brain code" management.
- To improve patient outcomes by ensuring timely and appropriate treatment for severe neurological events.
Main Methods:
- Development of a protocol based on a systematic review of current evidence.
- Standardization of diagnostic and therapeutic interventions for intracranial hypertension and herniation.
- Implementation of a stepwise management algorithm within the Emergency Neurological Life Support framework.
Main Results:
- A defined protocol for the evaluation of patients with elevated intracranial pressure.
- A structured algorithm for the management of acute brain herniation.
- Standardized treatment recommendations based on scientific evidence.
Conclusions:
- The Emergency Neurological Life Support protocol offers a standardized, evidence-based approach to managing intracranial hypertension and brain herniation.
- Implementing this protocol can lead to more consistent and effective care for patients experiencing "brain codes."
- This approach aims to reduce morbidity and mortality associated with these catastrophic neurological events.
Abstract:
Sustained intracranial hypertension and acute brain herniation are "brain codes," signifying catastrophic neurological events that require immediate recognition and treatment to prevent irreversible injury and death. As in cardiac arrest, a brain code mandates the organized implementation of a stepwise management algorithm. The goal of this Emergency Neurological Life Support protocol is to implement an evidence-based, standardized approach to the evaluation and management of patients with intracranial hypertension and/or herniation.

