Related Experiment Video
Updated: Feb 22, 2026
04:22
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
1.1K
Male hepatitis C patients' sexual functioning and its determinants
Christos K Triantos1, Aggeliki Tsintoni, Katerina Karaivazoglou
1Departments of aGastroenterology bInternal Medicine cDepartment of Psychiatry, School of Medicine, University of Patras, Patras, Greece.
European Journal of Gastroenterology & Hepatology
|September 16, 2017
Summary
Male hepatitis C virus patients experience sexual dysfunction, even without cirrhosis. Erectile function and satisfaction are linked to depression, anxiety, quality of life, and specific blood markers.
Area of Science:
- Hepatology
- Sexual Medicine
- Psychiatry
Background:
- Hepatitis C virus (HCV) infection can impact various aspects of patient health.
- Sexual dysfunction is a potential complication in male patients with chronic diseases.
Purpose of the Study:
- To investigate the prevalence of sexual impairment in male patients with hepatitis C virus.
- To identify factors associated with sexual dysfunction in this population.
Main Methods:
- A cross-sectional study involving 61 male HCV patients.
- Assessment of sexual functioning using the International Index of Erectile Function.
- Evaluation of health-related quality of life (HRQOL) and psychological distress (anxiety, depression).
Main Results:
- Clinically significant sexual dysfunction was observed, particularly in intercourse and overall satisfaction.
- Erectile function and desire correlated with depression, anxiety, HRQOL, platelet count, and international normalized ratio (INR).
- Orgasmic function and intercourse satisfaction showed significant associations with platelet count, INR, and psychological factors.
Conclusions:
- Hepatitis C is associated with sexual dysfunction in men, irrespective of cirrhosis.
- Specific domains of male sexual function are differentially correlated with psychological and biological markers.
Related Concept Videos
01:20Disorders of the Male Reproductive System
5.2K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.2K
01:23Infertility in Males
609
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
609
01:08Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
299
Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
299
01:22Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
225
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
225
01:26Sexually Transmitted Infections
1.3K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.3K
01:26Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
273
Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
273