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Updated: Feb 22, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Sleep Duration and Quality as Related to Left Ventricular Structure and Function.
Jae-Hon Lee1, Sung Keun Park, Jae-Hong Ryoo
1From the Department of Psychiatry (J.-H. Lee), Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea; Department of Psychiatry (J.-H. Lee, Mansur, McIntyre), University of Toronto, Ontario, Canada; Department of Psychiatry (J.-H. Lee), Kosleep Center, Seoul, Korea; Center for Cohort Studies (Park), Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea; Departments of Preventive Medicine (Ryoo, Oh, Jung), School of Medicine, Kyung Hee University, Seoul, Korea; Total Healthcare Center (Kang, Jung), Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea; Mood Disorders and Psychopharmacology Unit (Mansur, Y. Lee, McIntyre), University Health Network, Toronto, Ontario, Canada; Interdisciplinary Laboratory of Clinical Neurosciences (LINC) (Mansur), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), Brazil; Department of Medicine (Alfonsi), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Institute of Medical Science (Y. Lee), University of Tornoto, Ontario, Canada; Clinical Research Coordination Center (Shin), Office of Public Relations and Collaboration, National Cancer Center, Goyang, Korea; and Department of Pharmacology (McIntyre), University of Toronto, Ontario, Canada.
Short sleep duration, less than 7 hours, is linked to unfavorable left ventricular (LV) structural changes, including LV hypertrophy. This may partly explain how insufficient sleep increases cardiovascular risk.
Area of Science:
- Cardiology
- Sleep Medicine
- Public Health
Background:
- Inadequate sleep is a known risk factor for cardiovascular events.
- The precise relationship between sleep duration/quality and cardiac structure/function remains unclear.
Purpose of the Study:
- To investigate the association between sleep duration and quality with left ventricular (LV) diastolic dysfunction and structural deterioration.
- To determine if sleep impacts cardiac structure and function in healthy adults.
Main Methods:
- Cross-sectional study of 31,598 healthy Korean adults.
- Assessed sleep duration (self-reported, <7, 7-9, >9 hours, continuous) and quality (Pittsburg Sleep Quality Index).
- Utilized echocardiography to evaluate LV structure and function; logistic regression analyzed associations.
Main Results:
- Short sleep duration (<7 hours) was significantly associated with increased LV hypertrophy (LVH) and relative wall thickness.
- Each hour decrease in sleep duration correlated with greater LVH and increased relative wall thickness.
- No significant association was found between sleep parameters and LV diastolic function.
Conclusions:
- Short sleep duration is linked to adverse structural changes in the left ventricle.
- Adverse changes in cardiac structure may mediate the association between insufficient sleep and cardiovascular health outcomes.
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