[Preclinical tests of additive materials for personified endoprostheses of hand joints]
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Published on: May 14, 2020
G P Kotelnikov1, A V Kolsanov1, L T Volova1
1Samara State Medical University, Ministry of Healthcare of the Russian Federation, Samara, Russia.
Aim:
To evaluate the biocompatibility of additive materials for personified endoprostheses of hand joints in vivo.
Material And Methods:
We tested a material based on titanium that was implanted into muscles and bone tissue in experiment on rabbits. Follow-up was 30 and 90 days.
Results:
Implantation into muscle tissue is accompanied by reaction against foreign body followed by fibrosis without concomitant inflammation. Induction of osteogenesis and trabecular structures remodeling were detected after implantation into bone tissue.
Conclusion:
Biocompatibility of tested titanium-based material was confirmed.
