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Updated: Feb 22, 2026

Detecting Glycogen in Peripheral Blood Mononuclear Cells with Periodic Acid Schiff Staining
Published on: December 23, 2014
[Characteristics of lipid metabolism and the cardiovascular system in glycogenosis types I and III]
N V Polenova1, T V Strokova1, A V Starodubova1
1Federal Research Center of Nutrition and Biotechnology, Moscow, Russia.
Abstract:
Glycogen storage disease (GSD) is an inherited metabolic disorder characterized by early childhood lipid metabolic disturbances with potentially proatherogenic effects. The review outlines the characteristics of impaired lipid composition and other changes in the cardiovascular system in GSD types I and III. It analyzes the factors enabling and inhibiting the development of atherosclerosis in patients with GSD. The review describes the paradox of vascular resistance to the development of early atherosclerosis despite the proatherogenic composition of lipids in the patients of this group.
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