LH-RH treatment for cryptorchidism. Randomized study and 10-year follow-up results

A randomized study (LH-RH treatment or surgery) of 60 cryptorchid children between 2 and 9 years of age was performed. Testicular biopsy obtained in all patients undergoing orchiopexy showed histological changes compatible with cryptorchidism. Only maldescended and non-retractile testes were treated. LH-RH treatment was successful in 59% of the patients. Ten years later, 52% of testes remained descended. Thus LH-RH treatment is effective in achieving descent of true cryptorchid testes.