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Anomeric specificity of glucose-induced somatostatin secretion
V Leclercq-Meyer1, M C Woussen-Colle, C Lalieu
1Laboratory of Experimental Medicine, Brussels Free University, Belgium.
Abstract:
In isolated perfused rat pancreases, the alpha-anomer of D-glucose is more potent than beta-D-glucose not solely in stimulating insulin release and suppressing glucagon output, but also in causing somatostatin secretion.