Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and internal validation of the Meningioma Functional Outcome Risk and Counseling Estimator 6 score, a point-based prognostic tool for predicting 6-week functional independence after intracranial meningioma resection.

Journal of neurosurgery·2026
Same author

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months.

Epilepsia·2026
Same author

Real-world outcomes of responsive neurostimulation in patients with Lennox-Gastaut syndrome: A multicenter retrospective study.

Epilepsia open·2026
Same author

Parkinson's disease as a somato-cognitive action network disorder.

Nature·2026
Same author

Transcriptomic decoding of regional cortical vulnerability to drug-resistant epilepsy using 7T MRI.

Communications biology·2025
Same author

Centromedian region thalamic responsive neurostimulation mitigates idiopathic generalized and multifocal epilepsy with focal to bilateral tonic-clonic seizures.

Epilepsia·2024

Related Experiment Video

Updated: Feb 22, 2026

Deep Brain Stimulation with Simultaneous fMRI in Rodents
11:09

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

14.6K

Interventional MRI-Guided Deep Brain Stimulation Lead Implantation.

Philip S Lee1, Robert Mark Richardson1

  • 1Department of Neurological Surgery and Neurobiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Suite B400, Pittsburgh, PA 15213, USA.

Neurosurgery Clinics of North America
|September 18, 2017
PubMed
Summary

Interventional MRI-guided deep brain stimulation (DBS) offers precise targeting in the subthalamic nucleus and globus pallidus. This technique provides similar outcomes to awake procedures, expanding DBS accessibility for more patients.

Keywords:
Deep brain stimulationGlobus pallidusInterventional MRIIntraoperative MRIMovement disordersParkinson diseaseSubthalamic nucleus

More Related Videos

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

20.6K
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.5K

Related Experiment Videos

Last Updated: Feb 22, 2026

Deep Brain Stimulation with Simultaneous fMRI in Rodents
11:09

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

14.6K
Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

20.6K
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.5K

Area of Science:

  • Neurosurgery
  • Neurology
  • Medical Imaging

Background:

  • Functional anatomy of the subthalamic nucleus and globus pallidus is understood through microelectrode recording and imaging.
  • Anatomical targeting is validated for deep brain stimulation (DBS).

Purpose of the Study:

  • To describe considerations for interventional MRI (iMRI)-DBS implantation in the subthalamic nucleus and globus pallidus.
  • To highlight iMRI-DBS as a more anatomically accurate alternative to awake procedures.

Main Methods:

  • Utilizing interventional MRI (iMRI) for real-time guidance during electrode placement.
  • Focusing on anatomical targeting for subthalamic nucleus and globus pallidus DBS.

Main Results:

  • iMRI-DBS demonstrates superior anatomical accuracy compared to traditional awake DBS procedures.
  • Clinical outcomes and operative times are comparable to awake procedures.
  • iMRI-DBS expands treatment options for patients unable to undergo awake surgery.

Conclusions:

  • iMRI-DBS is a safe and effective method for targeting the subthalamic nucleus and globus pallidus.
  • This technique enhances DBS accessibility for a broader patient population.
  • Considerations include patient selection, electrode placement technique, outcomes, and potential complications.