Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamic Filtering Approach for the Online Preconcentration of Nanoplastics Using Capillary Electrophoresis.

Analytical chemistry·2026
Same author

Evaluation of non-targeted compound discovery capability of dehumidified alveolar exhaled breath collection by using stirbar sorptive extraction and multidimensional gas chromatography - mass spectrometry method.

Journal of chromatography. A·2025
Same author

Determining the hydrodynamic diameters of nanoplastics <i>via</i> short-end capillary zone electrophoresis-Taylor dispersion analysis in tandem.

The Analyst·2025
Same author

A sensitive, selective, and rapid fluorescent probe for thiophenol detection with a broad linear range and simple synthesis.

Talanta·2025
Same author

A Paper-Based Assay for the Determination of Total Antioxidant Capacity in Human Serum Samples.

Biosensors·2024
Same author

Recovery of Berry Natural Products Using Pyrene-Based MOF Solid Phase Extraction.

Chemistry (Weinheim an der Bergstrasse, Germany)·2024

Related Experiment Video

Updated: Feb 22, 2026

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood
08:58

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016

11.1K

Patterned polycaprolactone-filled glass microfiber microfluidic devices for total protein content analysis.

Gayan C Bandara1, Christopher A Heist1, Vincent T Remcho1

  • 1Department of Chemistry, Oregon State University, Corvallis, OR 97331, USA.

Talanta
|September 18, 2017
PubMed
Summary

Researchers developed a rapid method to create complex 2D and 3D microfluidic pathways on glass microfiber membranes. This technique modifies surface properties, enabling adaptable and inexpensive microfluidic device fabrication for various applications.

Keywords:
3D fabricationColorimetric detectionHuman serumPolycaprolactoneTotal protein analysisWicking microfluidics

More Related Videos

Digital Microfluidics for Automated Proteomic Processing
10:55

Digital Microfluidics for Automated Proteomic Processing

Published on: November 6, 2009

13.1K
High-throughput Protein Expression Generator Using a Microfluidic Platform
09:26

High-throughput Protein Expression Generator Using a Microfluidic Platform

Published on: August 23, 2012

12.3K

Related Experiment Videos

Last Updated: Feb 22, 2026

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood
08:58

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016

11.1K
Digital Microfluidics for Automated Proteomic Processing
10:55

Digital Microfluidics for Automated Proteomic Processing

Published on: November 6, 2009

13.1K
High-throughput Protein Expression Generator Using a Microfluidic Platform
09:26

High-throughput Protein Expression Generator Using a Microfluidic Platform

Published on: August 23, 2012

12.3K

Area of Science:

  • Microfluidics and Lab-on-a-Chip Technology
  • Materials Science and Engineering
  • Analytical Chemistry

Background:

  • Membrane-based microfluidic devices offer rapid, cost-effective analytical solutions.
  • Controlling surface hydrophilicity/hydrophobicity is crucial for device fabrication.
  • Glass microfiber (GMF) membranes are stable, inert, and inexpensive hydrophilic materials.

Purpose of the Study:

  • To develop a simple, rapid technique for fabricating complex 2D and 3D microfluidic pathways on a single membrane.
  • To functionalize GMF membranes with polycaprolactone (PCL) to alter their surface properties.
  • To demonstrate the adaptability and performance of the novel microfluidic fabrication method.

Main Methods:

  • Hydrophilic GMF membranes were filled with hydrophobic polycaprolactone (PCL).
  • PCL/GMF substrates were masked, and selective oxygen radical exposure created superhydrophilic regions.
  • A colorimetric total protein assay was used to validate the fabricated microfluidic device performance.

Main Results:

  • A novel, rapid fabrication technique for adaptable, complex multidimensional microfluidic pathways was successfully developed.
  • Surface chemistry modification enabled precise control over microfluidic pattern generation on PCL/GMF membranes.
  • The fabricated devices demonstrated effective performance in a protein concentration assay.

Conclusions:

  • This method provides a versatile platform for fabricating intricate microfluidic devices on GMF membranes.
  • The technique allows for the creation of both 2D and 3D microfluidic channels with controlled surface properties.
  • The developed approach is suitable for rapid prototyping and application in analytical chemistry and beyond.