Nano-hemoglobin film based sextet state biomemory device by cross-linked photosensitive hapten monomer

In this study, a biomemory device, consisting of hemoglobin (Hb) cross-linked by MACys-Ru(bipyr)₂-MACys) photosensitive monomer cross-linkers, which have memory effect through both Ru^3+/2+ in hapten monomer and Fe^3+/2+ in redox active center of Hb through multi-charge transfer mechanism, has been improved. Cyclic voltammetry (CV) has been used to determine the redox property of the Hb cross-linked MACys-Ru(bipyr)₂-MACys) hapten. Three memory functions, writing, reading and erasing of the fabricated biomemory device, have been accomplished by chronoamperometry (CA) and open-circuit potential amperometry (OCPA). The reliability and repeatability of the biodevice consisting of the p(Hb-co-MACys-Ru(bipyr)₂-MACys) sextet state bio-memory layer have been analysed. The Hb film based biodevice on gold electrodes has shown ≥ 2 months the retention time and switched until 10⁶ times continuous cycling without degradation in efficiency. Other hand, the topography of p(Hb-co-MACys-Ru(bipyr)₂-MACys) layer on the gold surface has investigated by scanning electron microscopy (SEM) and EDX data.