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Outcomes of Ahmed Glaucoma Valve Revision in Pediatric Glaucoma
Ahmed Mansour Al-Omairi1, Aliah H Al Ameri1, Sami Al-Shahwan1
1King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Insights
Ahmed glaucoma valve (AGV) revision in children shows high short-term success but a significant decrease in efficacy over time. Long-term outcomes for pediatric glaucoma surgery require further investigation.
Area of Science:
- Ophthalmology
- Pediatric Glaucoma Surgery
- Glaucoma Device Management
Background:
- Encapsulation of the Ahmed glaucoma valve (AGV) plate frequently causes elevated intraocular pressure (IOP) postoperatively, particularly in pediatric patients.
- While AGV revision outcomes in adults are documented, data for children remain limited.
Purpose of the Study:
- To evaluate the outcomes of Ahmed glaucoma valve revision surgery in children.
- To assess the efficacy and complications associated with AGV revision in a pediatric population.
Main Methods:
- A retrospective cross-sectional study involving a chart review of patients under 15 years old who underwent AGV revision.
- Minimum follow-up of 6 months, measuring IOP reduction, medication use, survival rates, and complications.
- Complete success defined as IOP ≤ 21 mm Hg without medication; qualified success as IOP ≤ 21 mm Hg with medication.
Main Results:
- 44 eyes were analyzed, primarily with primary congenital glaucoma (88.6%). Mean age was 6.7 years, with a median follow-up of 12 months.
- Postoperative IOP decreased from a mean of 30.4 mm Hg to 24.9 mm Hg at 6 months.
- Complete success rates declined from 100% at 1 month to 5.5% at 2 years. Qualified success rates showed approximately 50% survival at 1 year and 16% at 2 years, with a median survival time of 14 months. Recurrence of encapsulation was the most common complication (15.9%).
Conclusions:
- AGV revision in children demonstrates high initial success rates.
- However, the efficacy of AGV revision significantly diminishes with longer follow-up periods in pediatric glaucoma patients.
Purpose:
Encapsulation of the Ahmed glaucoma valve (AGV) plate is a common cause for postoperative elevation of intraocular pressure, especially in children. Many reports have described the outcomes of AGV revision in adults. However, the outcomes of AGV revision in children are poorly documented. The aim of this study was to determine the outcomes of AGV revision in children.
Design:
Retrospective cross-sectional study.
Methods:
A retrospective chart review of patients less than 15 years of age who underwent AGV revision with a minimum postoperative follow-up of 6 months was conducted. Outcome measures included reduction in intraocular pressure from baseline, survival analysis, and reduction in the number of antiglaucoma medications. Postoperative complications were also noted. Complete success was defined as an IOP of 21 mm Hg or less without medications, while qualified success was defined as having an IOP of 21 mm Hg or less with medications.
Results:
A total of 44 eyes met the inclusion criteria. Primary congenital glaucoma was present in 39 eyes (88.6%), aphakic glaucoma in 4 eyes (9.1%), and Peters anomaly-associated glaucoma in 1 eye (2.3%). The mean number of previous surgeries was 1.4, and the mean age was 6.7 years (range, 1.9-13 years) with a median follow-up of 12 months (range, 6-24 months). The IOP was reduced from a preoperative mean of 30.4 (± 10.3) to 24.9 (± 10.6) mm Hg at 6 months postoperatively. Kaplan-Meier analysis showed that the complete success rate at 1 month was 100% followed by a rapid decline at 6 months to 38.6%, 27.7% at 1 year, and 5.5% at 2 years. Qualified success rate was 100% at 1 month followed by a 6-month and 1-year survival rate of approximately 50% and a 2-year survival rate of approximately 16%. The median survival time was 14 months. No specific risk factors for failure were identified. Visual acuity remained unchanged following revision. The most common complication was recurrence of encapsulation with elevated IOP (15.9%). Other complications included hyphema (n = 3; 6.8%), endophthalmitis (n = 1; 2.3%), wound leak (n = 1; 2.3%), and choroidal detachment (n = 2; 4.5%).
Conclusion:
Although the short-term success rate of AGV revision in children is high, with longer follow-up the success rate decreases significantly.
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