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Updated: Feb 22, 2026

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Published on: July 26, 2019
Genetic affinity and the right to 'three-parent IVF'.
G Owen Schaefer1, Markus K Labude2
1Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Block MD 11 #02-03, 10 Medical Drive, Singapore, 117597, Singapore. medgos@nus.edu.sg.
Mitochondrial replacement therapy, or "three-parent IVF," is becoming a reality. Prohibitions on this procedure may infringe on procreative rights, particularly the interest in genetic affinity, supporting a right to this assisted reproductive technology.
Area of Science:
- Reproductive Medicine
- Bioethics
- Genetics
Background:
- Mitochondrial replacement therapy (MRT), or "three-parent IVF," is nearing clinical application following a live birth report.
- The UK permits MRT under regulation, but it is banned in many other nations.
- Prohibitions raise questions about procreative rights and the significance of genetic ties.
Purpose of the Study:
- To argue that bans on MRT may violate procreative rights.
- To explore the legal and ethical basis for a right to MRT, focusing on genetic affinity.
Main Methods:
- Legal and ethical analysis of procreative rights.
- Examination of the concept of genetic affinity and its legal recognition.
- Application of legal reasoning to the context of MRT.
Main Results:
- The interest in genetic affinity, recognized by courts globally, supports biological ties.
- Prohibitions on MRT may conflict with established procreative rights grounded in genetic affinity.
Conclusions:
- There is a compelling ethical and legal case for recognizing a right to "three-parent IVF."
- International legal trends emphasize genetic ties, bolstering arguments for access to MRT.
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