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Related Experiment Video

Updated: Feb 22, 2026

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
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Exercise in patients with multiple sclerosis.

Robert W Motl1, Brian M Sandroff1, Gert Kwakkel2

  • 1Department of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.

The Lancet. Neurology
|September 19, 2017
PubMed
Summary
This summary is machine-generated.

Exercise offers significant benefits for multiple sclerosis (MS) patients, yet physical activity levels remain low. Addressing research gaps and developing practical tools are crucial for integrating exercise into MS care.

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Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Exercise Science

Background:

  • Exercise is a vital rehabilitation strategy for multiple sclerosis (MS) patients, aiding symptom management, functional restoration, and overall quality of life.
  • Despite documented benefits, individuals with MS exhibit persistently low engagement in health-promoting physical activity compared to the general population.
  • This lack of engagement has remained unchanged for 25 years, highlighting a critical barrier in clinical practice.

Purpose of the Study:

  • To identify and address key limitations hindering the promotion of exercise in multiple sclerosis care through patient-clinician interactions.
  • To explore the need for enhanced evidence, mechanistic understanding, and practical frameworks for exercise implementation in MS.

Main Methods:

  • This study is a review and synthesis of existing evidence and clinical practice challenges related to exercise in multiple sclerosis.
  • It identifies limitations in the quality and scope of research, understanding of exercise mechanisms, and translation of evidence into practice.

Main Results:

  • Current evidence on exercise for MS is insufficient in quality and scope.
  • The mechanisms through which exercise benefits people with MS are not fully understood.
  • A practical framework and toolkit for translating exercise evidence into clinical practice are absent.

Conclusions:

  • Future research must address the identified limitations to effectively promote exercise in multiple sclerosis.
  • Developing a robust evidence base and practical implementation strategies is essential for integrating exercise into routine MS clinical care.
  • Overcoming these barriers will facilitate the inclusion of exercise as a standard component of care for individuals with MS.