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A light-up endoplasmic reticulum probe based on a rational design of red-emissive fluorogens with aggregation-induced
Chong-Jing Zhang1, Xiaolei Cai, Shidang Xu
1Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore, 117585, Singapore. cheliub@nus.edu.sg.
Chemical Communications (Cambridge, England)
|September 19, 2017
Abstract:
Fine-tuning electron acceptors through changing one cyano group to an amide generates a more stable and emissive fluorophore with the character of aggregation-induced emission. Conjugation between the new fluorophore and CFFKDEL generated an excellent ER targeting light-up probe with high specificity and good photostability.
