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Updated: Feb 22, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
The influence of additional nitrous oxide during rapid anesthetic induction with sevoflurane
Masaki Yurino1, Hitomi Kimura1
1Department of Anesthesiology and Resuscitology, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Hokkaido, Japan.
Abstract:
In this study, a vital capacity rapid inhalation induction technique was used, and 4.5% sevoflurane in 100% oxygen and with 66% nitrous oxide in oxygen were compared. Each anesthetic gas was used on a group of 17 unpre-medicated volunteers. The induction time of sevoflurane in nitrous oxide with oxygen and sevoflurane in oxygen were 55±10 s and 81±22 s (SD), respectively, (P<0.05). Notable cardiovascular instability was not observed in either group. Serious complications such as laryngospasm, breath holding, and excessive salivation were not observed in either group. In conclusion, the addition of nitrous oxide to sevoflurane in oxygen is a useful technique because there were no increases in complications during the accelerated rapidity of induction.
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