Related Experiment Video
Updated: Feb 22, 2026

Mechanical Ventilation Boot Camp Curriculum
Published on: March 12, 2018
Potential Acceptability of a Pediatric Ventilator Management Computer Protocol
Katherine A Sward1, Christopher J L Newth, Robinder G Khemani
11University of Utah College of Nursing, Salt Lake City, UT. 2Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT. 3Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 4Department of Pediatrics, University of Southern California, Keck School of Medicine, Los Angeles, CA. 5Division of Pediatric Critical Care, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT. 6Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 7Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 8Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL. 9Department of Pediatrics, University of Michigan, Ann Arbor, MI. 10Department of Pediatrics, Children's National Medical Center, Washington, DC. 11Department of Child Health, Phoenix Children's Hospital, Phoenix, AZ. 12Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 13Department of Pediatrics, Mattel Children's Hospital UCLA, Los Angeles, CA. 14Departments of Pediatrics and Biochemistry, Washington University School of Medicine, St. Louis, MO. 15Pediatric Trauma and Critical Injury Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD. 16Formerly Pediatric Trauma and Critical Injury Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD.
Insights
Physicians found ventilator management protocol recommendations acceptable overall, but disagreed on the specific size of ventilator setting adjustments for children with pediatric acute respiratory distress syndrome.
Area of Science:
- Pediatric Critical Care Medicine
- Respiratory Physiology
- Clinical Protocol Development
Background:
- Pediatric acute respiratory distress syndrome (PARDS) requires mechanical ventilation.
- Optimizing ventilator settings is crucial but complex.
- Standardized protocols may improve care but require clinician acceptance.
Purpose of the Study:
- To assess the acceptability and preferred granularity of ventilator management recommendations for PARDS.
- To inform the development of effective ventilator management protocols.
Main Methods:
- Online questionnaire administered to 122 physicians in eight Pediatric Intensive Care Units (PICUs).
- Physicians evaluated 50 clinical scenarios with protocol recommendations.
- Acceptability was measured based on scenario recommendations and provider characteristics.
Main Results:
- Overall, 80% of ventilator management recommendations were accepted.
- Acceptance varied by ventilator mode (e.g., HFOV 83%, PRVC 82%, PC 75%) and adjusted variable (e.g., PIP 88%, FiO2 86%, PEEP 69%).
- No significant variation in acceptance based on child size or age; preference for smaller PEEP changes noted.
Conclusions:
- While overall acceptance of PARDS ventilator management recommendations was high, consensus on the specific granularity of setting adjustments was lacking.
- A well-defined protocol could facilitate the evaluation of ventilator management strategies.
- Further research is needed to link protocol adherence to improved patient outcomes.
Objectives:
To examine issues regarding the granularity (size/scale) and potential acceptability of recommendations in a ventilator management protocol for children with pediatric acute respiratory distress syndrome.
Design:
Survey/questionnaire.
Setting:
The eight PICUs in the Collaborative Pediatric Critical Care Research Network.
Participants:
One hundred twenty-two physicians (attendings and fellows).
Interventions:
None.
Measurements And Main Results:
We used an online questionnaire to examine attitudes and assessed recommendations with 50 clinical scenarios. Overall 80% of scenario recommendations were accepted. Acceptance did not vary by provider characteristics but did vary by ventilator mode (high-frequency oscillatory ventilation 83%, pressure-regulated volume control 82%, pressure control 75%; p = 0.002) and variable adjusted (ranging from 88% for peak inspiratory pressure and 86% for FIO2 changes to 69% for positive end-expiratory pressure changes). Acceptance did not vary based on child size/age. There was a preference for smaller positive end-expiratory pressure changes but no clear granularity preference for other variables.
Conclusions:
Although overall acceptance rate for scenarios was good, there was little consensus regarding the size/scale of ventilator setting changes for children with pediatric acute respiratory distress syndrome. An acceptable protocol could support robust evaluation of ventilator management strategies. Further studies are needed to determine if adherence to an explicit protocol leads to better outcomes.
More Related Videos
06:57Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents
Published on: July 9, 2020
05:39Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Related Concept Videos
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Cardiopulmonary Resuscitation II: ACLS Airway Management