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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Updated: Feb 22, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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Essential tremor & Parkinson disease: Recognizing the differences.

Gwyn M Vernon1, Cheryl Leiningen, Cathi A Thomas

  • 1Gwyn M. Vernon is an NP at the University of Pennsylvania, Parkinson's Disease and Movement Disorders Center, Philadelphia, Pa., and national director of the Edmond J. Safra Visiting Nurse Faculty Program at the Parkinson's Foundation, Miami, Fla. Cathi A. Thomas is the program director of the Boston University Parkinson's Disease and Movement Disorders Center and assistant clinical professor in neurology at Boston University, Boston, Mass. Cheryl A. Leiningen is an assistant professor at the Monmouth University Marjorie K. Unterberg School of Nursing and Health Studies, West Long Branch, N.J. Susan R. Dunlop is the former associate director of the Johns Hopkins Parkinson's Disease and Movement Disorder Center, Baltimore, Md.

The Nurse Practitioner
|September 20, 2017
PubMed
Summary
This summary is machine-generated.

Essential tremor and Parkinson disease are common causes of adult tremor. This guide helps nurse practitioners assess tremor and distinguish between these two conditions using a case study approach.

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Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Tremor is a prevalent movement disorder affecting adults and the elderly.
  • Numerous tremor types and underlying conditions exist.

Observation:

  • This article focuses on the assessment and differential diagnosis of tremor.
  • A case study illustrates the diagnostic process for nurse practitioners (NPs).

Findings:

  • The article details the causes of tremor.
  • It provides a framework for differentiating essential tremor from Parkinson disease.

Implications:

  • Enhances NPs' ability to diagnose and manage tremor disorders.
  • Improves patient care for movement disorders.