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Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

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Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
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Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists01:28

Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists

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Prokinetic agents are specialized medications that stimulate gastrointestinal (GI) motility, promoting food movement through the GI tract. Dopamine, an inhibitory neurotransmitter, plays a significant role in this process, reducing GI motility and indirectly controlling the speed of digestion. Dopamine receptor antagonists, such as metoclopramide and domperidone, offer a unique advantage as prokinetic agents. By blocking the dopamine receptors, these drugs increase GI motility, improving food...
1.5K
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists01:23

Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists

1.1K
Serotonin, a crucial neurotransmitter synthesized by enterochromaffin cells, plays a cardinal role in regulating gastrointestinal (GI) motility. With over 90% of the body's total serotonin in the GI tract, its influence on digestive processes is profound. Serotonin is swiftly released upon various stimuli, such as food boluses or certain drugs, triggering intrinsic sensory neurons in the myenteric plexus and extrinsic vagal and spinal sensory neurons. This leads to the activation of the...
1.1K
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

499
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
499
Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

1.2K
Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
1.2K
Gastric Motility01:16

Gastric Motility

3.5K
Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
3.5K

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Related Experiment Video

Updated: Feb 22, 2026

Gastrointestinal Motility Monitor GIMM
08:15

Gastrointestinal Motility Monitor GIMM

Published on: December 1, 2010

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Motility disorders in infants.

I J N Koppen1, M A Benninga1, M M J Singendonk1

  • 1Department of Gastroenterology & Nutrition, Emma Children's Hospital, AMC, Amsterdam, The Netherlands.

Early Human Development
|September 21, 2017
PubMed
Summary
This summary is machine-generated.

Pediatric gastrointestinal motility disorders are common and varied. This review examines their development, focusing on how preterm birth impacts these conditions in infants.

Keywords:
ConstipationGastrointestinal motilityInfantsReflux

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Related Experiment Videos

Last Updated: Feb 22, 2026

Gastrointestinal Motility Monitor GIMM
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Published on: December 1, 2010

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Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
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Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines
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Area of Science:

  • Pediatric Gastroenterology
  • Developmental Biology

Background:

  • Gastrointestinal motility disorders are prevalent in children, presenting diverse symptoms from reflux to feeding issues.
  • These disorders can impact the entire digestive system, ranging in severity.

Purpose of the Study:

  • To review the embryologic and developmental aspects of gastrointestinal motility.
  • To specifically investigate the influence of preterm birth on the development of infant motility disorders.

Main Methods:

  • Literature review focusing on embryology, prenatal, and neonatal development of gastrointestinal motility.
  • Analysis of common congenital and acquired motility disorders in infancy.

Main Results:

  • Normal motility patterns in infants are established as a baseline.
  • The review details the impact of preterm birth on the incidence and presentation of these disorders.

Conclusions:

  • Understanding normal development is crucial for diagnosing motility disorders.
  • Preterm birth is a significant factor influencing the development of gastrointestinal motility issues in infants.