Related Experiment Video
Updated: Feb 22, 2026
08:03
Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
Published on: April 15, 2014
84.1K
[Pasteurella multocida meningoencephalitis in a 14-year-old child]
L Kuoch1, F Villedieu1, G Favaretto2
1Service de réanimation pédiatrique, pôle Femme-Enfant, CHU de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 9, France.
Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|September 21, 2017
Summary
Pasteurella multocida meningitis is rare, even without animal bites. This case highlights potential upper airway infection as a route for this serious bacterial meningitis.
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Background:
- Pasteurella multocida typically causes localized infections, often from animal bites.
- Meningitis caused by P. multocida is uncommon, primarily affecting the very young, elderly, or immunocompromised individuals.
Observation:
- A 14-year-old presented with bacterial meningitis symptoms, with P. multocida identified in cerebrospinal fluid.
- Despite third-generation cephalosporin treatment, the patient experienced clinical decline and a seizure, with imaging revealing pansinusitis but no brain complications.
Findings:
- The patient's condition ultimately improved without neurological deficits.
- The route of infection was determined to be through the upper airways, associated with sinusitis, not direct animal trauma.
Implications:
- This case underscores that P. multocida meningitis can occur via respiratory inoculation, expanding the known transmission pathways.
- Healthcare providers should consider P. multocida in meningitis cases, particularly those with sinusitis, irrespective of animal contact history.
