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Genetics of Tinnitus: Time to Biobank Phantom Sounds
Christopher R Cederroth1, Anna K Kähler2, Patrick F Sullivan2,3,4
1Experimental Audiology, Department of Physiology and Pharmacology, Karolinska InstitutetStockholm, Sweden.
Abstract:
Tinnitus is a common phantom sensation resulting most often from sensory deprivation, and for which little knowledge on the molecular mechanisms exists. While the existing evidence for a genetic influence on the condition has been until now sparse and underpowered, recent data suggest that specific forms of tinnitus have a strong genetic component revealing that not all tinnitus percepts are alike, at least in how they are genetically driven. These new findings pave the way for a better understanding on how phantom sensations are molecularly driven and call for international biobanking efforts.
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