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The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
Published on: October 9, 2013
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A novel and cheap method to correlate subjective and objective visual acuity by using the optokinetic response
Carlo Aleci1, Martina Scaparrotti2, Sabrina Fulgori2
1Service of Neuro-Ophthalmology, University of Turin, Turin Ophthalmic Hospital, Via Juvarra 19, 10100, Turin, Italy. carlo.aleci@unito.it.
International Ophthalmology
|September 21, 2017
Summary
The novel Oktotype device accurately estimates visual acuity in normal, poorly collaborative, and non-collaborative individuals. This optokinetic visual acuity estimator shows promise for predicting Snellen visual acuity.
Area of Science:
- Ophthalmology
- Optometry
- Visual Science
Background:
- Accurate visual acuity measurement is crucial for diagnosing and managing vision disorders.
- Assessing visual acuity in non-collaborative subjects, such as infants or individuals with cognitive impairments, presents significant challenges.
- Existing methods may be unreliable or difficult to administer in these populations.
Purpose of the Study:
- To introduce a novel optokinetic visual acuity estimator, the Oktotype.
- To evaluate the preliminary performance of the Oktotype in measuring visual acuity in poorly and non-collaborative subjects.
Main Methods:
- The Oktotype utilizes horizontally moving stimuli of decreasing size to elicit an optokinetic response.
- Visual acuity is determined by the smallest stimulus size that evokes this response.
- The study compared Oktotype measurements with subjective visual acuity and the Teller visual acuity test in different subject groups.
Main Results:
- The Oktotype demonstrated good agreement with subjective visual acuity in normal and poorly collaborative subjects (concordance correlation coefficient: 0.85 and 0.83).
- In non-collaborative subjects, the Oktotype showed strong agreement with the Teller test (concordance correlation coefficient: 0.79-0.85).
- The test-retest reliability of the Oktotype (K=0.82) was found to be very good, outperforming the Teller test (K=0.71).
Conclusions:
- The Oktotype is a promising tool for objective visual acuity estimation.
- It shows potential for predicting Snellen visual acuity, particularly in challenging populations like poorly and non-collaborative subjects.

