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[Herbgenomics].

Shi-Lin Chen1, Jing-Yuan Song2

  • 1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|September 21, 2017
PubMed
Summary
This summary is machine-generated.

Herbgenomics integrates genomics and other omics to explore the genetic basis of traditional Chinese medicine (TCM). This new field aims to uncover herb mechanisms for disease treatment and personalized medicine.

Keywords:
Herbgenomicsgenomicsomicsrandomized controlled trialtraditional Chinese medicine (TCM)

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Area of Science:

  • Integrative Biology
  • Genomics
  • Traditional Chinese Medicine

Background:

  • Traditional Chinese Medicine (TCM) has significant health benefits, but its molecular mechanisms are poorly understood.
  • Genomics and related 'omics' technologies offer new avenues for studying medicinal herbs.

Purpose of the Study:

  • Propose Herbgenomics, a new discipline integrating omics for herb research.
  • Uncover genetic information, regulatory networks, and molecular mechanisms of herbs in disease prevention and treatment.

Main Methods:

  • Herbgenomics encompasses structural genomics, functional genomics, transcriptomics, proteomics, metabonomics, epigenomics, and metagenomics.
  • Integrates genomic, transcriptomic, proteomic, and metabolomic data to predict metabolite pathways and regulation.

Main Results:

  • Herbgenomics provides a platform for analyzing complex herbal products and understanding herb quality.
  • Enables molecular herb identification and establishes herbal gene banks.

Conclusions:

  • Herbgenomics accelerates the application of advanced technologies in herbal research.
  • Revolutionizes the use and acceptance of traditional herbal medicines by elucidating targets and mechanisms for personalized medicine.