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The analysis of several nonopiate narcotic analgesics and cocaine in serum using high-performance liquid
L P Hackett1, L J Dusci, K F Ilett
1State Health Laboratory Services, Queen Elizabeth II Medical Centre, Nedlands, Western Australia.
Journal of Analytical Toxicology
|November 1, 1987
Abstract:
This paper describes a procedure for the quantitative determination of methadone, meperidine, normeperidine, pentazocine, propoxyphene, norpropoxyphene, and dextromoramide in serum down to levels of 10 micrograms/L and of cocaine down to 25 micrograms/L. The procedure involves a simple extraction technique and high-performance liquid chromatography and is suitable for use in overdose drug screening, forensic toxicology, therapeutic drug monitoring, and pharmacokinetic studies.