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Related Concept Videos

Instrument Calibration01:12

Instrument Calibration

868
Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
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Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

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A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
4.6K
Atomic Absorption Spectroscopy: Instrumentation01:22

Atomic Absorption Spectroscopy: Instrumentation

1.8K
An atomic absorption spectrophotometer (AAS) comprises several components: a radiation source, an atomizer, a monochromator, and a detector. The radiation source can be a hollow-cathode lamp (HCL) or an electrodeless-discharge lamp (EDL), both of which provide a narrow emission line of the required wavelength. However, some instruments use continuum sources and high-resolution monochromators to achieve a narrow range of radiation.
The atomizer used in AAS can be either a flame atomizer or an...
1.8K
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.4K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.4K
Calibration Curves: Correlation Coefficient01:10

Calibration Curves: Correlation Coefficient

5.0K
In a linear calibration curve, there is a value called the calibration coefficient, denoted by 'r,' which measures the strength and the direction of association between two variables. The correlation coefficient value ranges from −1 to +1. A value of +1 indicates a perfect positive linear correlation, −1 denotes a perfect negative correlation, and 0 implies no correlation between the two variables. A positive correlation value establishes that as one variable increases, the...
5.0K
Spectrophotometry: Introduction01:16

Spectrophotometry: Introduction

9.7K
Spectrophotometry is the quantitative measurement of the absorption, reflection, diffraction, or transmission of electromagnetic radiation through a material as a function of the intensity and wavelength of the radiation. A spectrophotometer is a device used to measure the change in the radiation intensity caused by its interaction with the material.
The essential components of a spectrophotometer include a source of electromagnetic radiation, a slot for placing a material to be analyzed, and a...
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A Review of Calibration Transfer Practices and Instrument Differences in Spectroscopy.

Jerome J Workman1,2

  • 11 316964 Unity Scientific, Milford, MA, USA.

Applied Spectroscopy
|September 21, 2017
PubMed
Summary
This summary is machine-generated.

Achieving identical results across multiple spectroscopic instruments using a single calibration remains challenging. This review examines common calibration transfer techniques and instrument-related uncertainties in spectroscopy.

Keywords:
Calibrationalignmentbias and slopemethod comparisonmultivariatetransferuncertainty

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Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Chemometrics

Background:

  • Calibration transfer is crucial for spectroscopic analysis (near-infrared, infrared, Raman).
  • Numerous methods exist, but consistent results across instruments are not yet fully achieved.
  • Precise calibration transfer aims to apply a single spectral database and model to multiple instruments with retained accuracy.

Purpose of the Study:

  • To review common calibration transfer techniques, focusing on instrument differences.
  • To discuss the mathematics of uncertainty in spectroscopic measurements between instruments.
  • To highlight the ongoing challenge of achieving identical analysis results across different instruments.

Main Methods:

  • Review of existing literature on calibration transfer techniques.
  • Analysis of mathematical principles underlying spectroscopic uncertainty.
  • Focus on instrument-specific factors affecting calibration transfer.

Main Results:

  • Despite various approaches, identical calibration transfer across instruments remains an elusive goal.
  • Instrument reproducibility, repeatability, reference values, and mathematics impact transfer success.
  • Understanding instrument differences is key to improving calibration transfer.

Conclusions:

  • Perfect calibration transfer, enabling indiscriminate use of a single model across instruments, is not yet a reality.
  • Further research is needed to address instrument-related uncertainties for robust spectroscopic calibration transfer.
  • This review provides insights into current techniques and challenges in spectroscopic calibration transfer.