Related Experiment Video
Updated: Feb 22, 2026

Assessment of Sensory Thresholds in Dogs Using Mechanical and Hot Thermal Quantitative Sensory Testing
Published on: October 26, 2021
Quantitative sensory testing for assessment of somatosensory function in human oral mucosa: a review
Pin Zhou1,2, Yaming Chen1,3, Jinglu Zhang1,3
1a Department of General Dentistry , Affiliated Hospital of Stomatology, Nanjing Medical University , Nanjing , China.
Objective:
This narrative review provides an overview of the quantitative sensory testing (QST) to assess somatosensory function in human oral mucosa.
Material And Methods:
A literature search was conducted in the PubMed database to identify studies in vivo on human oral mucosa using QST methods. A list of 149 articles was obtained and screened. A total of 36 relevant articles remained and were read in full text. Manual search of the reference lists identified eight additional relevant studies. A total of 44 articles were included for final assessment.
Results:
The included studies were divided into six categories according to the study content and objective. In each category, there was a great variety of aims, methods, participants and outcome measures. The application of QST has nevertheless helped to monitor somatosensory function in experimental models of intraoral pain, effects of local anesthesia, after oral and maxillofacial surgery and after prosthodontic and orthodontic treatment.
Conclusions:
QST has been proved to be sufficiently stable and reliable, and valuable information has been obtained regarding somatosensory function in healthy volunteers, special populations and orofacial pain patients. However, as most of the studies were highly heterogeneous, the results are difficult to compare quantitatively. A standardized intraoral QST protocol is recommended and expected to help advance a mechanism-based assessment of neuropathies and other intraoral pain conditions.
Related Concept Videos
Somatosensation
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Tactile and Chemical Senses
Sensory Perception: Organization of the Somatosensory System
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
Taste Buds and Receptors
Sensory Functions of the Skin
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...

