Related Experiment Videos
Core outcomes in periodontal trials: study protocol for core outcome set development.
Thomas J Lamont1, Jan E Clarkson2, David N J Ricketts2
1Dundee Dental School, Park Place, University of Dundee, Dundee, UK. t.lamont@dundee.ac.uk.
Trials
|September 22, 2017
Summary
This study develops a standardized core outcome set for periodontal disease research. This will improve the quality and comparability of clinical trials and systematic reviews on prevention and management.
Area of Science:
- Periodontology
- Clinical Trials
- Health Outcomes Research
Background:
- Heterogeneity in clinical outcome measures for periodontal disease hinders data synthesis for systematic reviews and guidelines.
- A standardized core outcome set is needed to improve the consistency of reporting in periodontal disease trials.
- This study aims to develop a core outcome set for effectiveness trials in periodontal disease prevention and management.
Framework:
- Utilizing existing outcomes identified from Cochrane systematic reviews on periodontal disease.
- Employing a consensus-driven approach involving key stakeholders: patients, dental professionals, researchers, and policymakers.
- Defining the core outcome set through an online e-Delphi process followed by a face-to-face meeting.
Implementation:
- Stakeholders will prioritize outcomes and provide feedback through multiple rounds of the e-Delphi process.
- Outcomes identified during the Cochrane review screening will be considered by stakeholders.
- Consensus on outcome inclusion will be determined using predefined rules after the final meeting.
Implications:
- The developed core outcome set will be relevant to all key stakeholders in periodontology.
- Findings will be disseminated to enhance clinical trials, systematic reviews, and clinical guidelines.
- Ultimately aims to improve the prevention and management strategies for periodontal diseases.