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Gingival mesenchymal stem cells.

Deepak Venkatesh1, K P Mohan Kumar2, Jyoti B Alur3

  • 1Department of Dentistry, ESIC Medical College, PGIMSR and Model Hospital, Bengaluru, Karnataka, India.

Journal of Oral and Maxillofacial Pathology : JOMFP
|September 22, 2017
PubMed
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Gingival mesenchymal stem/progenitor cells (GMSCs) offer promising regenerative and immunomodulatory potential. These abundant cells are easily accessible from the gingiva, presenting a unique source for therapeutic applications.

Area of Science:

  • Periodontology
  • Stem Cell Biology
  • Regenerative Medicine

Background:

  • The human gingiva exhibits remarkable scarless wound healing capabilities.
  • Gingival mesenchymal stem/progenitor cells (GMSCs) are a recently identified cell population within the gingival lamina propria.
  • GMSCs possess significant regenerative and immunomodulatory properties.

Purpose of the Study:

  • To summarize current scientific evidence on gingival mesenchymal stem/progenitor cells (GMSCs).
  • To highlight the unique characteristics and potential applications of GMSCs.

Main Methods:

  • Literature review of recent scientific publications on GMSCs.
  • Characterization of GMSCs' properties and isolation techniques.
Keywords:
Dental follicle progenitor cellsdental pulp stem cellsgingival mesenchymal stem cellsperiodontal ligament stem cellsstem cellstem cells from apical papillastem cells from exfoliated deciduous teeth

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Main Results:

  • GMSCs are abundant, easily accessible, and obtainable via minimally invasive procedures.
  • Compared to other mesenchymal stem/progenitor cell (MSC) sources, GMSCs present distinct advantages.
  • GMSCs demonstrate promising regenerative and immunomodulatory functions.

Conclusions:

  • Gingival mesenchymal stem/progenitor cells (GMSCs) represent a valuable and accessible cell source.
  • GMSCs hold significant potential for applications in regenerative medicine and periodontology.
  • Further research into GMSCs is warranted to explore their full therapeutic capacity.