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Collagen Cross- Linking for Paediatric Keratoconus.

Georgios D Panos1, Nikolaos Kozeis2, Miltiadis Balidis2

  • 1Department of Ophthalmology, Ipswich Hospital NHS Trust, University of Cambridge, Ipswich, Suffolk, UK.

The Open Ophthalmology Journal
|September 22, 2017
PubMed
Summary

Corneal crosslinking (CXL) effectively halts keratoconus progression in children, offering a vital treatment option for this age group. This review updates current literature on CXL

Keywords:
BiometryCοllagen crοss- linkingCοrneaPaediatric keratοcοnus

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Area of Science:

  • Ophthalmology
  • Corneal Surgery

Background:

  • Corneal crosslinking (CXL) has shown promise in halting keratoconus progression in adults since the late 1990s.
  • Keratoconus progression is more rapid and frequent in pediatric patients, necessitating prompt and effective interventions.

Purpose of the Study:

  • To review the current literature on the application of corneal crosslinking (CXL) in pediatric keratoconus patients.
  • To assess the efficacy and safety of CXL as a treatment to stop or slow keratoconus progression in children.

Main Methods:

  • Literature review of studies investigating corneal crosslinking in pediatric populations.
  • Analysis of treatment outcomes, including efficacy in halting disease progression and safety profiles.

Main Results:

  • Corneal crosslinking (CXL) has been increasingly applied to children, building on its success in adult keratoconus treatment.
  • Initial findings suggest CXL is a viable option for managing pediatric keratoconus.

Conclusions:

  • Corneal crosslinking (CXL) represents a significant advancement in managing pediatric keratoconus.
  • Further research and long-term data are essential to fully establish CXL's role in this age group.