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Functional Neuroimaging in Obesity Research.

Liliana Letra1,2, Daniela Pereira3,4, Miguel Castelo-Branco5

  • 1Institute of Physiology, Institute for Biomedical Imaging and Life Sciences-IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

Advances in Neurobiology
|September 22, 2017
PubMed
Summary

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Obesity impacts brain circuits involved in reward, emotion, and cognitive control. This research explores these neurobiological effects and introduces functional magnetic resonance imaging (fMRI) neurofeedback as a potential obesity treatment.

Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • Obesity is linked to altered neural activity in key brain regions.
  • Functional neuroimaging techniques like fMRI, PET, and SPECT reveal these changes.

Purpose of the Study:

  • To highlight the effects of obesity on specific neuronal circuits.
  • To discuss fMRI-based neurofeedback as a novel obesity treatment.

Main Methods:

  • Utilizing functional magnetic resonance imaging (fMRI) studies.
  • Reviewing positron emission tomography (PET) and single-photon emission computed tomography (SPECT) findings.

Main Results:

  • Obese individuals show aberrant activation in reward, emotion, memory, sensory, motor, and cognitive control circuits.
  • These patterns influence obesogenic behaviors.
Keywords:
Functional neuroimagingNeurofeedbackObesityPETSPECTfMRI

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Conclusions:

  • Obesity significantly affects brain function in critical neural circuits.
  • fMRI-based neurofeedback presents a promising avenue for obesity intervention.