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Updated: Feb 22, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Self-assembly of molecular ions via like-charge ion interactions and through-space defined organic domains
J S McNally1, X P Wang, C Hoffmann
1Idaho National Laboratory (INL) P.O. Box, 1625 MS 3531, Idaho Falls, ID 83415-3531, USA. aaron.wilson@inl.gov.
Abstract:
Reaction stoichiometry, dynamic light scattering, and DFT are used to explore tertiary ammonium bicarbonates that exist as ideal solutes and those that self-assemble. Self-assembling tertiary amines featured organic surfaces beyond a through-space defined sphere around the charge center. Like-charge hydrogen-bonded ion pairs (or anti-electrostatic hydrogen bonding (AEHB)) also play a role in the self-assembly and provide the first evidence of this bonding motif by bicarbonate in aqueous solution. A single crystal neutron structure of a tertiary ammonium bicarbonate featuring a bicarbonate dimer is presented.
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