Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Abnormal white matter microstructure among early adulthood smokers: a tract-based spatial statistics study.

Shuangkun Wang1, Long Zuo1, Tao Jiang1

  • 1a Department of Radiology, Beijing Chao-Yang Hospital , Capital Medical University , Beijing , China.

Neurological Research
|September 22, 2017
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Lasting Chemiluminescence Based on Functionalized Multicolor Protein Capsules for Multiple Visualization Detection of Avian Influenza Virus Biomarkers.

Analytical chemistry·2024
Same author

Spatio-temporal mapping of leaf area index in rice: spectral indices and multi-scale texture comparison derived from different sensors.

Frontiers in plant science·2024
Same author

Influence of autonomic nervous dysfunction on eating during hemodialysis sessions: An observational study.

Medicine·2024
Same author

A high-safety lithium-ion battery electrospun separator with Si<sub>3</sub>N<sub>4</sub>-assisted sulfonated poly(ether ether ketone) for regulating lithium flux.

Journal of colloid and interface science·2024
Same author

Intelligent Analysis of Avian Influenza Virus Biomarkers Based on Chemiluminescence Resonance Energy Transfer and DNA Logic Analysis.

ACS applied materials & interfaces·2024
Same author

Blue emission-dominated NaYbF<sub>4</sub>@NaYF<sub>4</sub>:2%Ho@NaYF<sub>4</sub> upconversion nanoparticles for detecting ascorbic acid.

Nanoscale·2024

Chronic smoking alters white matter (WM) integrity in young adults, affecting brain structure. These microstructural changes in WM may serve as potential biomarkers for smoking-related neurological effects.

Area of Science:

  • Neuroscience
  • Radiology
  • Public Health

Background:

  • Cigarette smoking is a significant risk factor for central nervous system diseases.
  • The impact of chronic smoking on white matter (WM) integrity in early adulthood is not fully understood.

Purpose of the Study:

  • To investigate whole-brain WM microstructure in early adulthood chronic smokers.
  • To explore structural correlates of behaviorally relevant features in smokers.

Main Methods:

  • Compared diffusion tensor imaging (DTI)-derived indices (FA, MD, AD, RD) between smokers (n=19) and controls (n=23).
  • Utilized whole-brain tract-based spatial statistics (TBSS).
  • Correlated DTI indices with pack-years and Fagerström Test for Nicotine Dependence.
Keywords:
Diffusion tensor imagingcigarette smokerstract-based spatial statisticswhite matter

Related Experiment Videos

Main Results:

  • Smokers exhibited increased fractional anisotropy (FA) in several left-hemisphere WM regions, including the superior longitudinal fasciculus (SLF) and external capsule (EC).
  • Decreased radial diffusivity (RD) was observed in the left SLF of smokers.
  • Negative correlation found between left EC FA and pack-years; positive correlation between left SLF RD and pack-years.

Conclusions:

  • Early adulthood smokers display microstructural WM alterations.
  • The correlation between cumulative smoking exposure (pack-years) and WM changes suggests potential for WM properties as biomarkers.