Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

3.6K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
3.6K
Menopause01:28

Menopause

5.0K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
5.0K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

494
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
494
Regulation of Stroke Volume01:27

Regulation of Stroke Volume

5.3K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

End-to-End Mandarin Speech Reconstruction Based on Ultrasound Tongue Images Using Deep Learning.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2025
Same author

Hybrid Quantum Deep Learning With Superpixel Encoding for Earth Observation Data Classification.

IEEE transactions on neural networks and learning systems·2025
Same author

Comparison of different approaches applied for surgical correction of partial anomalous pulmonary venous connection.

Cardiology in the young·2025
Same author

Enhanced heart sound anomaly detection via WCOS: a semi-supervised framework integrating wavelet, autoencoder and SVM.

Frontiers in neuroinformatics·2025
Same author

Inhibition of soluble epoxide hydrolase ameliorates cerebral blood flow autoregulation and cognition in alzheimer's disease and diabetes-related dementia rat models.

GeroScience·2025
Same author

Developing Soluplus®-Based Microparticle Amorphous Solid Dispersions with High Drug Loading for Enhanced Celecoxib Dissolution via Electrospraying.

AAPS PharmSciTech·2025

Related Experiment Video

Updated: Feb 22, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.6K

Menopause and Ischemic Stroke: A Brief Review.

Shashank Shekhar1,2, Olivia K Travis3, Xiaochen He3

  • 1Department of Neurology, University of Mississippi Medical Center, USA.

MOJ Toxicology
|September 23, 2017
PubMed
Summary

Sex hormones influence stroke risk, offering protection before menopause but increasing it afterward. Hormone replacement therapy

Keywords:
EpidemiologyGenderHormonesReceptorsStroke

More Related Videos

Author Spotlight: Innovative Techniques and Future Directions in Stroke Research
04:46

Author Spotlight: Innovative Techniques and Future Directions in Stroke Research

Published on: May 5, 2023

5.6K
Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area
09:08

Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area

Published on: February 2, 2017

17.2K

Related Experiment Videos

Last Updated: Feb 22, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.6K
Author Spotlight: Innovative Techniques and Future Directions in Stroke Research
04:46

Author Spotlight: Innovative Techniques and Future Directions in Stroke Research

Published on: May 5, 2023

5.6K
Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area
09:08

Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area

Published on: February 2, 2017

17.2K

Area of Science:

  • Neuroscience
  • Endocrinology
  • Cardiovascular Research

Background:

  • Ischemic stroke is a major global health concern.
  • Females exhibit a premenopausal stroke protection, which diminishes post-menopause.
  • Sex differences in stroke incidence and severity are not fully understood.

Purpose of the Study:

  • To explore the role of sex steroid hormones in stroke pathophysiology.
  • To investigate estrogen receptor-dependent signaling in stroke.
  • To examine factors influencing hormone replacement therapy outcomes in stroke.

Main Methods:

  • Review of existing literature on sex hormones and stroke.
  • Discussion of molecular mechanisms of estrogen signaling.
  • Analysis of discrepancies in hormone replacement therapy effects.

Main Results:

  • Estrogen and progesterone show neuroprotective effects in animal models.
  • Clinical outcomes of hormone replacement therapy for stroke risk reduction are inconsistent.
  • Sex hormone-dependent pathways are implicated in stroke risk modulation.

Conclusions:

  • Sex steroid hormones play a complex role in stroke, with premenopausal protection and postmenopausal increase in risk.
  • Estrogen receptor signaling pathways are critical in stroke.
  • Further research is needed to clarify the discrepant effects of hormone replacement therapy.