Related Experiment Video
Updated: Feb 22, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
SELF-INFLICTED LASER HANDHELD LASER-INDUCED MACULOPATHY: A NOVEL OCULAR MANIFESTATION OF FACTITIOUS DISORDER
Alessandro Rabiolo1, Riccardo Sacconi2, Chiara Giuffrè1
1Department of Ophthalmology, IRCCS San Raffaele, University Vita-Salute San Raffaele, Milan, Italy.
Purpose:
To report a case of factitious self-inflicted handheld laser-induced maculopathy.
Methods:
A 29-year-old man presented to our clinic complaining of a step-wise progressive loss of vision that abruptly began in his left eye but then became bilateral. He underwent comprehensive ocular examination, including visual acuity testing, biomicroscopic, dilated funduscopic examination, structural optical coherence tomography, en face structural optical coherence tomography, optical coherence tomography angiography, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography.
Results:
Visual acuity was 20/200 in both eyes. Although the multimodal imaging was highly consistent with handheld laser-induced maculopathy, the patient continued to deny this behavior.
Conclusion:
Self-inflicted handheld laser-induced maculopathy may be a novel manifestation of factitious disorder. Clinical suspicion for this should remain high in the presence of the signature multimodal retinal findings despite denial by the patient. This category of patients could benefit from psychiatric referral, to prevent further ocular or extra-ocular self-injury.

