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Related Experiment Video

Updated: Feb 22, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
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Choroidal thickness in traumatic optic neuropathy.

Ju-Yeun Lee1, Doo-Ri Eo1, Kyung-Ah Park1

  • 1a Department of Ophthalmology , Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul , South Korea.

Current Eye Research
|September 23, 2017
PubMed
Summary

Patients with traumatic optic neuropathy (TON) have a thicker choroid in affected eyes compared to unaffected eyes. This finding may indicate impaired blood circulation and vascular remodeling, offering insights into TON

Keywords:
Choroidspectral-domain optical coherence tomographytraumatic optic neuropathy

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Area of Science:

  • Ophthalmology
  • Neuroscience

Background:

  • Traumatic optic neuropathy (TON) is a vision-threatening condition resulting from optic nerve injury.
  • Understanding the underlying pathophysiology of TON is crucial for developing effective treatments.

Purpose of the Study:

  • To investigate choroidal thickness variations in patients diagnosed with indirect traumatic optic neuropathy (TON).
  • To compare choroidal thickness between affected and unaffected eyes in TON patients and with a control group.

Main Methods:

  • Utilized enhanced-depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT) scans.
  • Analyzed horizontal and vertical scans of the fovea in unilateral TON patients within two weeks of injury.
  • Measured choroidal thickness at nine distinct locations.

Main Results:

  • Affected eyes in TON patients exhibited significantly thicker choroids (13-23%) compared to unaffected fellow eyes at multiple locations.
  • The mean difference in choroidal thickness between eyes was significantly greater in the TON group than in controls.
  • No significant difference in subfoveal choroidal thickness was observed between TON and control eyes.

Conclusions:

  • Eyes affected by TON demonstrate regional choroidal thickening relative to unaffected eyes.
  • This thickening may stem from compromised blood circulation and vascular remodeling in the optic nerve head and choroid.
  • The findings contribute to a better understanding of TON's pathophysiology.