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Proteus Syndrome With a Cranial Intraosseous Lipoma
Erik M Wolfswinkel1, Thomas A Imahiyerobo, J Gordon McComb
1*Division of Plastic and Reconstructive Surgery, Keck School of Medicine at University of Southern California, Los Angeles, CA †Division of Plastic Surgery, New York Presbyterian Hospital-Columbia University Medical Center, New York, NY ‡Division of Neurosurgery, Children's Hospital Los Angeles §Department of Neurological Surgery ||Department of Pathology and Pediatrics, Keck School of Medicine ¶Center for Craniofacial Molecular Biology, University of Southern California #Division of Genomic Medicine, Center for Personalized Medicine **Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, Los Angeles, CA.
Abstract:
Intraosseous lipomas are almost exclusively seen in the long bones. Presence in the craniofacial skeleton is extremely rare. A 7-year-old male is presented with a marked craniofacial deformation from a bony tumor containing an intraosseous lipoma. This finding established a clinical diagnosis of Proteus syndrome. Given the size of the tumor, producing an extensive deformity, three-dimensional modeling was used to generate a three-dimensional printed implant. The process to achieve a successful outcome is herein described.
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