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Related Experiment Videos

Do surgical packs cause peritoneal adhesions?

R H Down, R Whitehead, J M Watts

    The Australian and New Zealand Journal of Surgery
    |June 1, 1979
    PubMed
    Summary

    Surgical sponges can cause significant postoperative peritoneal adhesions, regardless of whether they are used wet or dry. Further research is recommended to establish the adhesogenic potential of all intraabdominal products before marketing.

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    Area of Science:

    • Surgical innovation
    • Biomaterials science
    • Surgical pathology

    Background:

    • Intraabdominal packs (sponges) are widely used in surgery.
    • No published data exist on the adhesion-producing properties of surgical sponges.
    • Peritoneal adhesions are a significant cause of postoperative morbidity.

    Purpose of the Study:

    • To evaluate the adhesogenic potential of two commercially available surgical packs.
    • To determine if the use of wet or dry sponges impacts adhesion formation.
    • To establish a reliable animal model for testing surgical materials.

    Main Methods:

    • Utilized the Porton rat model, known to reliably produce peritoneal adhesions.
    • Conducted a randomized control trial comparing two brands of surgical packs.
    • Assessed adhesion incidence in packs used both wet and dry.

    Main Results:

    • Both tested surgical pack brands induced a significant incidence of postoperative peritoneal adhesions.
    • Adhesion formation was observed irrespective of whether the packs were used wet or dry.
    • The Porton rat model proved effective for evaluating adhesogenic properties.

    Conclusions:

    • Commercially available surgical packs possess significant adhesogenic potential.
    • The method of sponge use (wet or dry) did not alter adhesion formation.
    • Mandatory preclinical animal model testing of intraabdominal products is recommended prior to marketing.

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