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Updated: Feb 22, 2026

Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
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Published on: June 28, 2019

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Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics

Kunhong Xiao1, Jinpeng Sun2

  • 1Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA; Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA; Biomedical Mass Spectrometry Center, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Cellular Signalling
|September 24, 2017
PubMed

Keywords:
7TMRArrestinBiased agonismBiased agonistDrug discoveryGPCRMass spectrometryPharmacologyProteomicsβ-Arrestin

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