A comparative study: deep anterior lamellar keratoplasty for corneal dystrophies using two different donor stromal...

This study aimed to present a comparison of early postoperative results of deep anterior lamellar keratoplasty (DALK) surgery performed using the two different corneal graft sources.

This retrospective clinical study included the surgery performed on 26 eyes of 26 patients who underwent DALK for the stromal dystrophies. At the time of surgery, donor stromal tissue for DALK was sourced using the two different preparatory techniques. For 14 cases (Group 1), the donor grafts were prepared quickly by removing the descemet's membrane (DM) without much care after the exposure of the bare DM in the recipient cornea. For 12 cases (Group 2), the grafts for DALK surgery had already been prepared during a previous descemet's membrane endothelial keratoplasty (DMEK).

The groups differed statistically regarding the blue staining of the grafts at the time of surgery and on the first day post-DALK. The first day after surgery, 14 (100%) grafts were clear in Group 1, while eight (66.7%) grafts were clear and four (33.3%) were edematous in Group 2 (p = 0.019). Bubbling was performed in three (25.0% of Group 2) of the four cases on the first day post-DALK, while none of the patients in Group 1 underwent this procedure (p = 0.47). The postoperative increase in visual acuity was higher in Group 1 in the early postoperative period (p = 0.012).

During the early postoperative period, complications (as graft edema, detachment, re-bubbling) were observed more frequently in the DALK operations performed with stromal tissue having blue stain remaining from the DMEK performed on the same day and in the same session.