Related Experiment Video
Updated: Feb 22, 2026

08:18
Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
Published on: October 4, 2024
1.5K
The effect of prism on preferred retinal locus
David Lewerenz1,2, Daniel Blanco1,3, Chase Ratzlaff1,4
1Oklahoma College of Optometry, Northeastern State University, Tahlequah, Oklahoma, USA.
Clinical & Experimental Optometry
|September 24, 2017
Summary
Base-up prism may shift the preferred retinal locus (PRL) in patients with central scotoma, but the shift is not predictable. Further research is needed to determine the clinical significance of this small shift in visual function.
Area of Science:
- Ophthalmology
- Visual Neuroscience
- Low Vision Rehabilitation
Background:
- The effect of prism, particularly base-up prism, on the retinal area used for fixation in central scotoma patients remains controversial.
- This pilot study investigates the impact of base-up prism on the preferred retinal locus (PRL) using microperimetry.
Purpose of the Study:
- To evaluate the effect of base-up prism on the fixation locus (PRL) in individuals with central scotoma.
- To determine if prism can predictably relocate the PRL for improved visual function.
Main Methods:
- Microperimetry was used to assess the PRL in 13 visually impaired subjects with central scotoma.
- Measurements were taken under four conditions: no lens, control lens, 6Δ base-up prism, and 10Δ base-up prism.
- PRL location was quantified in degrees relative to the optic disc.
Main Results:
- The preferred retinal locus (PRL) did not significantly differ with no lens versus a control lens.
- Base-up prisms (6Δ and 10Δ) induced a superior shift in the PRL in 84.6% of cases.
- The magnitude of the PRL shift was significantly less than the prism power, and vertical and horizontal movements were comparable.
Conclusions:
- Base-up prism generally shifts the PRL towards the prism base, but the relocation is not consistently predictable.
- The observed shift in PRL may not be clinically significant, warranting further investigation.
- Additional research is required to ascertain the functional impact of prism-induced PRL shifts in low vision patients.
Related Concept Videos
Photoreceptors and Visual Pathways
9.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
9.5K
Anatomy of the Eyeball
10.1K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
10.1K
Focusing of Light in the Eye
6.5K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
6.5K
The Retina
77.0K
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
77.0K

