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Dodging Endosomes: Effective Cytosolic Antibody Delivery

Dennis W P M Löwik1

  • 1Radboud University Nijmegen, Institute for Molecules and Materials, Bio-organic Chemistry, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands.

Chembiochem : a European Journal of Chemical Biology
|September 24, 2017
PubMed
Summary

New methods enable antibody delivery into the cell cytosol. These approaches bypass cellular defenses by crossing the plasma membrane or escaping endosomes for therapeutic applications.

Keywords:
antibodiescell-penetrating peptidescytosolic delivery

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